Diagnostic biosensor device for pathogen detection
In the past, detection systems to identify pathogens have been expensive, complicated to use, are limited in the panel of organisms that can be detected, and have high background and low sensitivity. We propose to develop a device consisting of multiple parallel microcantilevers that will be used to detect pathogens in fluid-based environments.
These microfabricated devices will allow samples to be surveyed and monitored in real time. They will be highly sensitive and extremely accurate. The parallel MEMS cantilever-based platform that we propose to develop will be based on nucleic acid pathogen signatures that are identified using software that was developed at the University of Maryland Center for Bioinformatics and Computational Biology.
David Mosser